Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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SRS Ovarian Hendrix Cluster Number 14 (147 genes) This page contains all miRNA mediated regulation and functional enrichment for SRS Ovarian Hendrix cluster number 14. Information about ovarian cancer can be found on Wikipedia, and further information about the "SRS Ovarian Hendrix" dataset can be found in Hendrix et al., 2006. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 zzz999 hsa-mir-1290 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0001501 skeletal system development 14 GO:0001503 ossification 14 GO:0001525 angiogenesis 14 GO:0001568 blood vessel development 17 GO:0001944 vasculature development 18 GO:0001957 intramembranous ossification 3 GO:0002544 chronic inflammatory response 3 GO:0006928 cellular component movement 26 GO:0007155 cell adhesion 36 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 13 GO:0007179 transforming growth factor beta receptor signaling pathway 10 GO:0007275 multicellular organismal development 67 GO:0008218 bioluminescence 2 GO:0008283 cell proliferation 30 GO:0008285 negative regulation of cell proliferation 14 GO:0009605 response to external stimulus 28 GO:0009611 response to wounding 28 GO:0009653 anatomical structure morphogenesis 41 GO:0009887 organ morphogenesis 18 GO:0010755 regulation of plasminogen activation 3 GO:0010757 negative regulation of plasminogen activation 3 GO:0010761 fibroblast migration 2 GO:0016477 cell migration 23 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 8 GO:0022008 neurogenesis 23 GO:0022610 biological adhesion 36 GO:0030154 cell differentiation 42 GO:0030193 regulation of blood coagulation 5 GO:0030195 negative regulation of blood coagulation 4 GO:0030198 extracellular matrix organization 7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 5 GO:0030855 epithelial cell differentiation 9 GO:0031589 cell-substrate adhesion 11 GO:0031638 zymogen activation 4 GO:0031639 plasminogen activation 3 GO:0032101 regulation of response to external stimulus 13 GO:0032501 multicellular organismal process 82 GO:0032502 developmental process 68 GO:0040011 locomotion 31 GO:0042127 regulation of cell proliferation 24 GO:0048468 cell development 24 GO:0048513 organ development 38 GO:0048514 blood vessel morphogenesis 16 GO:0048519 negative regulation of biological process 45 GO:0048523 negative regulation of cellular process 42 GO:0048646 anatomical structure formation involved in morphogenesis 17 GO:0048699 generation of neurons 22 GO:0048705 skeletal system morphogenesis 9 GO:0048731 system development 59 GO:0048856 anatomical structure development 61 GO:0048869 cellular developmental process 43 GO:0048870 cell motility 23 GO:0050793 regulation of developmental process 23 GO:0050818 regulation of coagulation 5 GO:0050819 negative regulation of coagulation 4 GO:0051674 localization of cell 23 GO:0051893 regulation of focal adhesion assembly 3 GO:0051917 regulation of fibrinolysis 3 GO:0051918 negative regulation of fibrinolysis 3 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-1290 TargetScan GO:0001501 skeletal system development 2 14 147 39 0.7741081 hsa-mir-1290 TargetScan GO:0001503 ossification 3 14 147 39 0.537438 hsa-mir-1290 TargetScan GO:0001525 angiogenesis 2 14 147 39 0.7741081 hsa-mir-1290 TargetScan GO:0001568 blood vessel development 2 17 147 39 0.8834838 hsa-mir-1290 TargetScan GO:0001944 vasculature development 3 18 147 39 0.7605122 hsa-mir-1290 TargetScan GO:0001957 intramembranous ossification 1 3 147 39 0.1719164 hsa-mir-1290 TargetScan GO:0002544 chronic inflammatory response 0 3 147 39 0.6063818 hsa-mir-1290 TargetScan GO:0006928 cellular component movement 8 26 147 39 0.2136961 hsa-mir-1290 TargetScan GO:0007155 cell adhesion 8 36 147 39 0.6706147 hsa-mir-1290 TargetScan GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 3 13 147 39 0.469128 hsa-mir-1290 TargetScan GO:0007179 transforming growth factor beta receptor signaling pathway 2 10 147 39 0.5238443 hsa-mir-1290 TargetScan GO:0007275 multicellular organismal development 18 67 147 39 0.3920919 hsa-mir-1290 TargetScan GO:0008218 bioluminescence 1 2 147 39 0.06905228 hsa-mir-1290 TargetScan GO:0008283 cell proliferation 8 30 147 39 0.3933652 hsa-mir-1290 TargetScan GO:0008285 negative regulation of cell proliferation 5 14 147 39 0.129303 hsa-mir-1290 TargetScan GO:0009605 response to external stimulus 8 28 147 39 0.2993941 hsa-mir-1290 TargetScan GO:0009611 response to wounding 5 28 147 39 0.8194468 hsa-mir-1290 TargetScan GO:0009653 anatomical structure morphogenesis 11 41 147 39 0.3926208 hsa-mir-1290 TargetScan GO:0009887 organ morphogenesis 3 18 147 39 0.7605122 hsa-mir-1290 TargetScan GO:0010755 regulation of plasminogen activation 1 3 147 39 0.1719164 hsa-mir-1290 TargetScan GO:0010757 negative regulation of plasminogen activation 1 3 147 39 0.1719164 hsa-mir-1290 TargetScan GO:0010761 fibroblast migration 0 2 147 39 0.46156 hsa-mir-1290 TargetScan GO:0016477 cell migration 6 23 147 39 0.4086432 hsa-mir-1290 TargetScan GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 2 8 147 39 0.3586109 hsa-mir-1290 TargetScan GO:0022008 neurogenesis 7 23 147 39 0.2321603 hsa-mir-1290 TargetScan GO:0022610 biological adhesion 8 36 147 39 0.6706147 hsa-mir-1290 TargetScan GO:0030154 cell differentiation 11 42 147 39 0.4359653 hsa-mir-1290 TargetScan GO:0030193 regulation of blood coagulation 3 5 147 39 0.01771265 hsa-mir-1290 TargetScan GO:0030195 negative regulation of blood coagulation 2 4 147 39 0.05726577 hsa-mir-1290 TargetScan GO:0030198 extracellular matrix organization 1 7 147 39 0.5973197 hsa-mir-1290 TargetScan GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 1 5 147 39 0.3998813 hsa-mir-1290 TargetScan GO:0030855 epithelial cell differentiation 1 9 147 39 0.7436199 hsa-mir-1290 TargetScan GO:0031589 cell-substrate adhesion 2 11 147 39 0.5980386 hsa-mir-1290 TargetScan GO:0031638 zymogen activation 1 4 147 39 0.286567 hsa-mir-1290 TargetScan GO:0031639 plasminogen activation 1 3 147 39 0.1719164 hsa-mir-1290 TargetScan GO:0032101 regulation of response to external stimulus 4 13 147 39 0.237978 hsa-mir-1290 TargetScan GO:0032501 multicellular organismal process 22 82 147 39 0.3910177 hsa-mir-1290 TargetScan GO:0032502 developmental process 18 68 147 39 0.4309357 hsa-mir-1290 TargetScan GO:0040011 locomotion 9 31 147 39 0.275192 hsa-mir-1290 TargetScan GO:0042127 regulation of cell proliferation 7 24 147 39 0.2777042 hsa-mir-1290 TargetScan GO:0048468 cell development 6 24 147 39 0.4625593 hsa-mir-1290 TargetScan GO:0048513 organ development 8 38 147 39 0.7469662 hsa-mir-1290 TargetScan GO:0048514 blood vessel morphogenesis 2 16 147 39 0.853472 hsa-mir-1290 TargetScan GO:0048519 negative regulation of biological process 11 45 147 39 0.5656898 hsa-mir-1290 TargetScan GO:0048523 negative regulation of cellular process 10 42 147 39 0.5995559 hsa-mir-1290 TargetScan GO:0048646 anatomical structure formation involved in morphogenesis 4 17 147 39 0.4878539 hsa-mir-1290 TargetScan GO:0048699 generation of neurons 7 22 147 39 0.1899166 hsa-mir-1290 TargetScan GO:0048705 skeletal system morphogenesis 2 9 147 39 0.4433325 hsa-mir-1290 TargetScan GO:0048731 system development 15 59 147 39 0.5208563 hsa-mir-1290 TargetScan GO:0048856 anatomical structure development 15 61 147 39 0.6002915 hsa-mir-1290 TargetScan GO:0048869 cellular developmental process 12 43 147 39 0.3232695 hsa-mir-1290 TargetScan GO:0048870 cell motility 6 23 147 39 0.4086432 hsa-mir-1290 TargetScan GO:0050793 regulation of developmental process 7 23 147 39 0.2321603 hsa-mir-1290 TargetScan GO:0050818 regulation of coagulation 3 5 147 39 0.01771265 hsa-mir-1290 TargetScan GO:0050819 negative regulation of coagulation 2 4 147 39 0.05726577 hsa-mir-1290 TargetScan GO:0051674 localization of cell 6 23 147 39 0.4086432 hsa-mir-1290 TargetScan GO:0051893 regulation of focal adhesion assembly 0 3 147 39 0.6063818 hsa-mir-1290 TargetScan GO:0051917 regulation of fibrinolysis 2 3 147 39 0.01762024 hsa-mir-1290 TargetScan GO:0051918 negative regulation of fibrinolysis 2 3 147 39 0.01762024

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